TOXICITY OF 1, 2‐DIMETHYLHYDRAZINE IN MICE: EFFECT OF DIET AND DEVELOPMENT OF TOLERANCE

N. J. TEMPLE; S. M. EL‐KHATIB

doi:10.1111/j.1745-4565.1985.tb00499.x

TOXICITY OF 1, 2‐DIMETHYLHYDRAZINE IN MICE: EFFECT OF DIET AND DEVELOPMENT OF TOLERANCE

N. J. TEMPLE
, S. M. EL‐KHATIB

Centre for Science

Universidad Central del Caribe

Research output: Contribution to journal › Journal Article › peer-review

2 Citations (Scopus)

Abstract

The effect of diet on the lethality of 1, 2‐dimethylhydrazine (DMH) injections was investigated using Swiss mice. Mortality was highest when mice were fed a nutrient‐diluted/high‐fat diet, was intermediate with a nutrient‐diluted/low‐fat diet and was lowest with laboratory chow. Wheat bran was not protective. Mice developed tolerance to DMH after receiving several injections of progressively increasing dose.

Original language	English
Pages (from-to)	77-81
Number of pages	5
Journal	Journal of Food Safety
Volume	7
Issue number	2
DOIs	https://doi.org/10.1111/j.1745-4565.1985.tb00499.x
Publication status	Published - Sep. 1985

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title = "TOXICITY OF 1, 2‐DIMETHYLHYDRAZINE IN MICE: EFFECT OF DIET AND DEVELOPMENT OF TOLERANCE",

abstract = "The effect of diet on the lethality of 1, 2‐dimethylhydrazine (DMH) injections was investigated using Swiss mice. Mortality was highest when mice were fed a nutrient‐diluted/high‐fat diet, was intermediate with a nutrient‐diluted/low‐fat diet and was lowest with laboratory chow. Wheat bran was not protective. Mice developed tolerance to DMH after receiving several injections of progressively increasing dose.",

author = "TEMPLE, \{N. J.\} and EL‐KHATIB, \{S. M.\}",

year = "1985",

month = sep,

doi = "10.1111/j.1745-4565.1985.tb00499.x",

language = "English",

volume = "7",

pages = "77--81",

number = "2",

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TY - JOUR

T1 - TOXICITY OF 1, 2‐DIMETHYLHYDRAZINE IN MICE

T2 - EFFECT OF DIET AND DEVELOPMENT OF TOLERANCE

AU - TEMPLE, N. J.

AU - EL‐KHATIB, S. M.

PY - 1985/9

Y1 - 1985/9

N2 - The effect of diet on the lethality of 1, 2‐dimethylhydrazine (DMH) injections was investigated using Swiss mice. Mortality was highest when mice were fed a nutrient‐diluted/high‐fat diet, was intermediate with a nutrient‐diluted/low‐fat diet and was lowest with laboratory chow. Wheat bran was not protective. Mice developed tolerance to DMH after receiving several injections of progressively increasing dose.

AB - The effect of diet on the lethality of 1, 2‐dimethylhydrazine (DMH) injections was investigated using Swiss mice. Mortality was highest when mice were fed a nutrient‐diluted/high‐fat diet, was intermediate with a nutrient‐diluted/low‐fat diet and was lowest with laboratory chow. Wheat bran was not protective. Mice developed tolerance to DMH after receiving several injections of progressively increasing dose.

UR - https://www.scopus.com/pages/publications/84987472600

U2 - 10.1111/j.1745-4565.1985.tb00499.x

DO - 10.1111/j.1745-4565.1985.tb00499.x

M3 - Journal Article

AN - SCOPUS:84987472600

SN - 0149-6085

VL - 7

SP - 77

EP - 81

JO - Journal of Food Safety

JF - Journal of Food Safety

IS - 2

ER -

TOXICITY OF 1, 2‐DIMETHYLHYDRAZINE IN MICE: EFFECT OF DIET AND DEVELOPMENT OF TOLERANCE

Abstract

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