TY - JOUR
T1 - TOXICITY OF 1, 2‐DIMETHYLHYDRAZINE IN MICE
T2 - EFFECT OF DIET AND DEVELOPMENT OF TOLERANCE
AU - TEMPLE, N. J.
AU - EL‐KHATIB, S. M.
PY - 1985/9
Y1 - 1985/9
N2 - The effect of diet on the lethality of 1, 2‐dimethylhydrazine (DMH) injections was investigated using Swiss mice. Mortality was highest when mice were fed a nutrient‐diluted/high‐fat diet, was intermediate with a nutrient‐diluted/low‐fat diet and was lowest with laboratory chow. Wheat bran was not protective. Mice developed tolerance to DMH after receiving several injections of progressively increasing dose.
AB - The effect of diet on the lethality of 1, 2‐dimethylhydrazine (DMH) injections was investigated using Swiss mice. Mortality was highest when mice were fed a nutrient‐diluted/high‐fat diet, was intermediate with a nutrient‐diluted/low‐fat diet and was lowest with laboratory chow. Wheat bran was not protective. Mice developed tolerance to DMH after receiving several injections of progressively increasing dose.
UR - http://www.scopus.com/inward/record.url?scp=84987472600&partnerID=8YFLogxK
U2 - 10.1111/j.1745-4565.1985.tb00499.x
DO - 10.1111/j.1745-4565.1985.tb00499.x
M3 - Journal Article
AN - SCOPUS:84987472600
SN - 0149-6085
VL - 7
SP - 77
EP - 81
JO - Journal of Food Safety
JF - Journal of Food Safety
IS - 2
ER -