TY - JOUR
T1 - Systemic cytokine response to three bouts of eccentric exercise
AU - Cornish, Stephen M.
AU - Johnson, Steven T.
N1 - Funding Information:
This study was kindly supported by the Sports Science Association of Alberta.
PY - 2014/4
Y1 - 2014/4
N2 - This research examined the changes in inflammatory cytokines interleukin 6 (IL-6), IL-1β, IL-10, as well as muscle force, muscle soreness, thigh circumference, and range of motion in response to 3 bouts of eccentric knee extension. Ten males were recruited to participate. The participants performed eccentric exercise on 3 consecutive days on the knee extensors on the right leg separated by 24 h. Participants performed 6 sets of 10 repetitions of isokinetic eccentric knee extension at 120° per second. Blood was sampled before and after each exercise bout and 24 h after the final exercise bout. Muscle isometric force, delayed onset muscle soreness (DOMS), thigh circumference, and range of motion were evaluated before and after each exercise bout and 24 h after the final exercise bout. There were no statistically significant differences noted for the changes in isometric strength, thigh circumference, and range of motion, or IL-6 over the 4days (all p>0.05). On the second day and third day there was a significant increase noted in DOMS as compared with baseline (p<0.05). These results suggest that 3 consecutive days of eccentric exercise results in DOMS but does not produce a sustained systemic inflammatory reaction or changes in muscle function.
AB - This research examined the changes in inflammatory cytokines interleukin 6 (IL-6), IL-1β, IL-10, as well as muscle force, muscle soreness, thigh circumference, and range of motion in response to 3 bouts of eccentric knee extension. Ten males were recruited to participate. The participants performed eccentric exercise on 3 consecutive days on the knee extensors on the right leg separated by 24 h. Participants performed 6 sets of 10 repetitions of isokinetic eccentric knee extension at 120° per second. Blood was sampled before and after each exercise bout and 24 h after the final exercise bout. Muscle isometric force, delayed onset muscle soreness (DOMS), thigh circumference, and range of motion were evaluated before and after each exercise bout and 24 h after the final exercise bout. There were no statistically significant differences noted for the changes in isometric strength, thigh circumference, and range of motion, or IL-6 over the 4days (all p>0.05). On the second day and third day there was a significant increase noted in DOMS as compared with baseline (p<0.05). These results suggest that 3 consecutive days of eccentric exercise results in DOMS but does not produce a sustained systemic inflammatory reaction or changes in muscle function.
KW - Delayed onset muscle soreness
KW - Eccentric exercise
KW - Inflammation
KW - Interleukin 6
UR - http://www.scopus.com/inward/record.url?scp=84899930498&partnerID=8YFLogxK
U2 - 10.1016/j.rinim.2014.04.002
DO - 10.1016/j.rinim.2014.04.002
M3 - Journal Article
AN - SCOPUS:84899930498
VL - 4
SP - 23
EP - 29
JO - Results in Immunology
JF - Results in Immunology
IS - 1
ER -