TY - JOUR
T1 - In search of quality evidence for lifestyle management and glycemic control in children and adolescents with type 2 diabetes
T2 - A systematic review
AU - Johnson, Steven T.
AU - Newton, Amanda S.
AU - Chopra, Meera
AU - Buckingham, Jeanette
AU - Huang, Terry T.K.
AU - Franks, Paul W.
AU - Jetha, Mary M.
AU - Ball, Geoff D.C.
N1 - Funding Information:
STJ, MC, JB, and TT-KH received no external support. PWF is supported by Västerbotten’s Health Authority (ALF strategic appointment 2006-2009), the Swedish Heart-Lung Foundation (20070633), and the Swedish Diabetes Association (DIA2006-013). ASN is supported by a Career Development Award from the Canadian Child Health Clinician Scientist Program (funded by the Canadian Institutes of Health Research [CIHR]). GDCB is supported by a Population Health Investigator Award from Alberta Innovates - Health Solutions and a New Investigator Award from CIHR. These study sponsors did not play any role in this research or in the decision to submit the paper for publication. Contents of the publication do not necessarily represent the views or policies of the National Institutes of Health.
PY - 2010/12/23
Y1 - 2010/12/23
N2 - Background: Our purpose was to evaluate the impact of lifestyle behavior modification on glycemic control among children and youth with clinically defined Type 2 Diabetes (T2D).Methods: We conducted a systematic review of studies (randomized trials, quasi-experimental studies) evaluating lifestyle (diet and/or physical activity) modification and glycemic control (HbA1c). Our data sources included bibliographic databases (EMBASE, CINAHL®, Cochrane Library, Medline®, PASCAL, PsycINFO®, and Sociological Abstracts), manual reference search, and contact with study authors. Two reviewers independently selected studies that included any intervention targeting diet and/or physical activity alone or in combination as a means to reduce HbA1c in children and youth under the age of 18 with T2D.Results: Our search strategy generated 4,572 citations. The majority of citations were not relevant to the study objective. One study met inclusion criteria. In this retrospective study, morbidly obese youth with T2D were treated with a very low carbohydrate diet. This single study received a quality index score of < 11, indicating poor study quality and thus limiting confidence in the study's conclusions.Conclusions: There is no high quality evidence to suggest lifestyle modification improves either short- or long-term glycemic control in children and youth with T2D. Additional research is clearly warranted to define optimal lifestyle behaviour strategies for young people with T2D.
AB - Background: Our purpose was to evaluate the impact of lifestyle behavior modification on glycemic control among children and youth with clinically defined Type 2 Diabetes (T2D).Methods: We conducted a systematic review of studies (randomized trials, quasi-experimental studies) evaluating lifestyle (diet and/or physical activity) modification and glycemic control (HbA1c). Our data sources included bibliographic databases (EMBASE, CINAHL®, Cochrane Library, Medline®, PASCAL, PsycINFO®, and Sociological Abstracts), manual reference search, and contact with study authors. Two reviewers independently selected studies that included any intervention targeting diet and/or physical activity alone or in combination as a means to reduce HbA1c in children and youth under the age of 18 with T2D.Results: Our search strategy generated 4,572 citations. The majority of citations were not relevant to the study objective. One study met inclusion criteria. In this retrospective study, morbidly obese youth with T2D were treated with a very low carbohydrate diet. This single study received a quality index score of < 11, indicating poor study quality and thus limiting confidence in the study's conclusions.Conclusions: There is no high quality evidence to suggest lifestyle modification improves either short- or long-term glycemic control in children and youth with T2D. Additional research is clearly warranted to define optimal lifestyle behaviour strategies for young people with T2D.
UR - http://www.scopus.com/inward/record.url?scp=78650311712&partnerID=8YFLogxK
U2 - 10.1186/1471-2431-10-97
DO - 10.1186/1471-2431-10-97
M3 - Journal Article
C2 - 21182791
AN - SCOPUS:78650311712
VL - 10
JO - BMC Pediatrics
JF - BMC Pediatrics
M1 - 97
ER -