Dietary fats and coronary heart disease

Research output: Contribution to journalJournal Articlepeer-review

42 Citations (Scopus)


The prevention and treatment of coronary heart disease (CHD) necessitates vigorous dietary intervention so as to lower the serum cholesterol level by at least 6%. Greater decreases in serum cholesterol can bring about reversal of atherosclerosis. The critical dietary change is the reduction in intake of saturated fat and cholesterol. Some of this fat may be replaced by unsaturated fats, especially monounsaturated fat (olive or canola oil). Fish and the omega-3 fats they contain may also be useful for the prevention of CHD. The benefits of omega-3 fats occur within a few months and probably involve an anti-thrombotic effect. There is evidence that the intake of trans-fatty acids formed by the hydrogenation of oils should be reduced as they are associated with CBD. Hypolipidaemic drugs may be useful for persons at very high risk of CHD but should generally be avoided for primary prevention.

Original languageEnglish
Pages (from-to)261-268
Number of pages8
JournalBiomedicine and Pharmacotherapy
Issue number6-7
Publication statusPublished - 1996


  • Coronary heart disease
  • Omega-3 fatty acids
  • Trans fatty acids


Dive into the research topics of 'Dietary fats and coronary heart disease'. Together they form a unique fingerprint.

Cite this