TY - JOUR
T1 - A case of contagious toxicity? Isoprostanes as potential emerging contaminants of concern
AU - Gaw, Sally
AU - Glover, Chris N.
N1 - Publisher Copyright:
© 2016 Elsevier B.V.
PY - 2016/8/1
Y1 - 2016/8/1
N2 - Isoprostanes are useful biomarkers of human and animal health, being representative of oxidative stress processes, and having biological impacts associated with toxicity and disease. Isoprostanes are also chemically stable, a property facilitating population-level health assessments through wastewater sampling. However, as biologically-active entities, the presence of isoprostanes in domestic effluents could have toxic impacts on biota in receiving environments. As such it is proposed that isoprostanes are emerging organic contaminants of particular concern. Fish and aquatic invertebrates may be affected by the presence of isoprostanes in wastewaters through mechanisms such as reproductive impairment, cardiovascular disturbance and/or oxidative stress. This would represent a unique scenario of "contagious" toxicity, whereby human health has a direct toxicological consequence on aquatic animal health.
AB - Isoprostanes are useful biomarkers of human and animal health, being representative of oxidative stress processes, and having biological impacts associated with toxicity and disease. Isoprostanes are also chemically stable, a property facilitating population-level health assessments through wastewater sampling. However, as biologically-active entities, the presence of isoprostanes in domestic effluents could have toxic impacts on biota in receiving environments. As such it is proposed that isoprostanes are emerging organic contaminants of particular concern. Fish and aquatic invertebrates may be affected by the presence of isoprostanes in wastewaters through mechanisms such as reproductive impairment, cardiovascular disturbance and/or oxidative stress. This would represent a unique scenario of "contagious" toxicity, whereby human health has a direct toxicological consequence on aquatic animal health.
KW - Aquatic organisms
KW - Emerging contaminants
KW - Isoprostanes
KW - Wastewater
UR - http://www.scopus.com/inward/record.url?scp=84964330019&partnerID=8YFLogxK
U2 - 10.1016/j.scitotenv.2016.04.005
DO - 10.1016/j.scitotenv.2016.04.005
M3 - Comment/debate
C2 - 27102276
AN - SCOPUS:84964330019
SN - 0048-9697
VL - 560-561
SP - 295
EP - 298
JO - Science of the Total Environment
JF - Science of the Total Environment
ER -